https://www.resources.pitt.edu All HSCRF Clinical Research Cores Facilities _Clinical Agents_ Immunologic Monitoring and Cellular Products Laboratory The Immunologic Monitoring and Cellular Products Laboratory (IMCPL) operates 12 clean rooms and focuses on IND manufacturing under cGMP/cGTP. Operations are monitored 24/7 by expert staff. The facility director specializes in and collaborates on preclinical research development involving process conceptualization, technology transfer and testing implementation on human cell-based drugs for clinical trials. Immunological monitoring services are available to support clinical trials. The facility is a FACT-, CLIA-, CAP-, and FDA-accredited laboratory. Peptide and Peptoid Synthesis Facility The Peptide and Peptoid Synthesis Core provides comprehensive services for peptide & peptoid synthesis, custom modifications, purification, and characterization to research programs at the University of Pittsburgh and UPMC. Pre-clinical In Vivo Imaging Facility, Hillman Cancer Center The Preclinical In Vivo Imaging Facility at UPMC Hillman Cancer Center offers MR, PET-CT, optical and ultrasound for small animals. _Clinical Research Centers_ Pediatric Clinical and Translational Research Center (PCTRC) The Pediatric Clinical And Translational Research Center (PCTRC) is a unique multidisciplinary setting that provides physicians the opportunity to investigate childhood diseases in a controlled environment on both an inpatient and outpatient basis. Pediatric Clinical Research Services The Pediatric Clinical Research Services group (PCRS) provides clinical research management, budget development, experienced clinical research coordinators, and regulatory support in both the inpatient and outpatient setting. These programs assist investigators in enrolling subjects, scheduling and conducting research visits, data entry, and sponsor engagement at UPMC Magee-Women's Hospital via the Newborn Research Support Service program (NuRSERy) and at UPMC Children’s Hospital of Pittsburgh via the Clinical Research Support Services program (CRSS). This cooperative model provides a bridge between the two institutions and a service solution that permits ongoing engagement as study participants age. The Clinical and Translational Resaerch Center of Magee-Women's Research Institute The Clinical and Translational Resaerch Center of Magee-Women's Research Institute is an outpatient facility supporting clinical and translational research in women's health. Facilities include interview and exam rooms, as well as laboratory support for processing biological specimens. The CTRC also facilitates newborn and infant research visits. UPMC Montefiore University Hospital Clinical and Translational Research Center The UPMC Montefiore University Hospital Clincal and Translational Research Centerprovides state-of-the-art infrastructure, inpatient and outpatient facilities, specialized equipment, and experienced staff to support clinical and translational research. Administrative staff maintain rigorous oversight of all studies and assist investigators with every aspect of research from study design and budget development through implementation. _Clinical Trial Data Support_ Biostatistics Facility, UPMC Hillman Cancer Center The Biostatics Facility at UPMC Hillman Cancer Center provides statistical and computational methods for design, execution, analysis, and reporting of cancer-related research studies and trials including biomarker analysis and grant development. Shadyside, HCC Center for Biostatistics & Qualitative Methodology (CBQM) The Center for Biostatistics and Qualitative Methodology provides cutting-edge expertise and research infrastructure across 4 key Cores: Biostatistics, Data Management & Information Systems, Qualitative Analysis, and Data Coordination. Epidemiology Data Center, Pitt Public Health The Epidemiology Data Center at Pitt Public Health provides a research environment in which complex health questions can be explored and answered using the combined tools of biology and statistics. EDC establishes collaborations with clinical researchers to design, conduct and analyze multicenter, randomized clinical trials and epidemiological studies. Health Services Research Data Center (HSRDC) The Health Sciences Research Data Center is a HIPAA compliant secure computing environment where study teams can store data and do analytics from anywhere with internet access. Teams work in a Windows virtual desktop with memory, storage, and computing power dedicated to each user. Knowledgeable facility staff can provide data management, help with regulatory documents like DUAs, maintain systems compliance, and custom application development. _Clinical Trial Operational Support_ Multidisciplinary Acute Care Clinical Research Organization The Multidisciplinary Acute Care Clinical Research Organization provides all services needed to conduct clinical trials. Staffed by specialists in the areas of regulatory compliance, contracting, laboratory services, screening/enrolling, and trial/data management MACRO provides year-round 24/7 support for studies in critical care, emergency medicine, surgery, pediatrics, and other limited areas based on need. _Human Subject Imaging_ CMU-Pitt Brain Imaging Data Generation & Education Center The CMU-Pitt Brain Imaging Data Generation & Education Center is a research-dedicated neuroimaging facility, with a focus on advanced data analytics and basic science research. It is designed exclusively to support basic science research and the next generation of brain scientists. RRID: SCR_023356 In Vivo Imaging Facility, UPMC Hillman Cancer Center (clinical research) The UPMC Hillman Cancer Center In Vivo Imaging Facility provides novel quantitative imaging assessments and metrics that include but not limited to standard FDA-approved clinical trial imaging assessments (such as RECIST, iRECIST, irRECIST, iiRC, RANO, Lugano, etc) to evaluate cancer therapy and more advanced AI imaging assessments using radiomics, radiogenomics, and AI-driven imaging biomarkers to enhance diagnostic, monitoring and post-therapy predictions and assessments. Magnetic Resonance Research Center The Magnetic Resonance Research Center is dedicated to the development and application of magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) for medical and biological research. MRRC is whole-body imaging capable with specialty in anatomical MRI imaging of brain, spine, extremities, liver, bladder as well as functional MRI to study cognitive, sensory, and motor function in the brain. Positron Emission Tomography (PET) Research Center The Positron Emission Tomography (PET) Research Center provides PET imaging for clinical research and pre-clinical studies. Radiotracer production and development are also available. _Regulatory and Recruitment Assistance_ Clinical and Translational Science Institute, Core Services The Clinical and Translational Science Institute offers specialist research services, as well as funding and educational opportunities, through the following cores: Regulatory Knowledge and Support, Trial Implementation and Enrollment, Community PARTners, Pilot Funding, Biomedical Informatics, Biostatistics, Epidemiology and Research Design, Clinical Research Facilities, Implementation Lab, Innovation, Research Participation, Team Science and Workforce Development, IMPaCT Core, and Human-Centered Design. Magee-Womens Hospital Clinical and Translational Research Center The Magee-Womens Hospital Clinical and Translational Research Center is a dedicated outpatient facility that supports a wide range of clinical and translational research. Staffed by experienced research personnel and nurses, the unit includes spaces designed to accommodate flexible sigmoidoscopies, medication infusions, pharmacokinetic sampling, EKGs, biological specimen processing, and other research-related assessments. Multidisciplinary Acute Care Clinical Research Organization The Multidisciplinary Acute Care Clinical Research Organization provides all services needed to conduct clinical trials. Staffed by specialists in the areas of regulatory compliance, contracting, laboratory services, screening/enrolling, and trial/data management MACRO provides year-round 24/7 support for studies in critical care, emergency medicine, surgery, pediatrics, and other limited areas based on need. Pediatric Clinical Research Services The Pediatric Clinical Research Services group (PCRS) provides clinical research management, budget development, experienced clinical research coordinators, and regulatory support in both the inpatient and outpatient setting. These programs assist investigators in enrolling subjects, scheduling and conducting research visits, data entry, and sponsor engagement at UPMC Magee-Women's Hospital via the Newborn Research Support Service program (NuRSERy) and at UPMC Children’s Hospital of Pittsburgh via the Clinical Research Support Services program (CRSS). This cooperative model provides a bridge between the two institutions and a service solution that permits ongoing engagement as study participants age. Pitt Biospecimen Core (PBC) The Pitt Biospecimen Core provides human sample procurement in multiple UPMC hospitals across Pittsburgh. Standard operating procedures for procurement and processing are developed for each project in partnership with each study's principal investigator. A rigorous quality assurance program ensures SOP compliance. In addition to specimen banking and pathology consultation, research histology services by expert histology specialists are also available. Pittsburgh Pepper Center  The Pepper Research Network on Aging (PRNA) maintains two registries that are available for Pepper-approved researchers who are conducting aging-related research at the University of Pittsburgh. These registries include the Community Research Connection and the Platinum Senior-Living Registry based in long-term senior housing. Women’s Health Practice-Based Research Network  The Women’s Health Practice-Based Research Network (WHPBRN) promotes collaboration between practitioners and clinical investigators to improve women’s health. _Specimen Processing_ Biobehavioral Oncology Facility The Biobehavioral Oncology Facility at UPMC Hillman Cancer Center provides wet lab support for specimen processing and a wide range of assays for biobehavioral researchers lacking access to wet lab space and/or necessary expertise. Magee Obstetric Maternal and Infant Database and Biobank The Magee Obstetric Maternal and Infant (MOMI) Database and Biobank contains a collection of obstetric biological materials from prenatal visits through delivery along with annotated clinical information. In addition to banked specimens, assistance with prospective specimen collection can be provided. Magee-Womens Hospital Clinical and Translational Research Center The Magee-Womens Hospital Clinical and Translational Research Center is a dedicated outpatient facility that supports a wide range of clinical and translational research. Staffed by experienced research personnel and nurses, the unit includes spaces designed to accommodate flexible sigmoidoscopies, medication infusions, pharmacokinetic sampling, EKGs, biological specimen processing, and other research-related assessments. Pediatric Clinical and Translational Research Center (PCTRC) The Pediatric Clinical And Translational Research Center (PCTRC) is a unique multidisciplinary setting that provides physicians the opportunity to investigate childhood diseases in a controlled environment on both an inpatient and outpatient basis. Pediatric Clinical Research Services The Pediatric Clinical Research Services group (PCRS) provides clinical research management, budget development, experienced clinical research coordinators, and regulatory support in both the inpatient and outpatient setting. These programs assist investigators in enrolling subjects, scheduling and conducting research visits, data entry, and sponsor engagement at UPMC Magee-Women's Hospital via the Newborn Research Support Service program (NuRSERy) and at UPMC Children’s Hospital of Pittsburgh via the Clinical Research Support Services program (CRSS). This cooperative model provides a bridge between the two institutions and a service solution that permits ongoing engagement as study participants age. Pitt Biospecimen Core (PBC) The Pitt Biospecimen Core provides human sample procurement in multiple UPMC hospitals across Pittsburgh. Standard operating procedures for procurement and processing are developed for each project in partnership with each study's principal investigator. A rigorous quality assurance program ensures SOP compliance. In addition to specimen banking and pathology consultation, research histology services by expert histology specialists are also available. The Clinical and Translational Resaerch Center of Magee-Women's Research Institute The Clinical and Translational Resaerch Center of Magee-Women's Research Institute is an outpatient facility supporting clinical and translational research in women's health. Facilities include interview and exam rooms, as well as laboratory support for processing biological specimens. The CTRC also facilitates newborn and infant research visits. UPMC Montefiore University Hospital Clinical and Translational Research Center The UPMC Montefiore University Hospital Clincal and Translational Research Centerprovides state-of-the-art infrastructure, inpatient and outpatient facilities, specialized equipment, and experienced staff to support clinical and translational research. Administrative staff maintain rigorous oversight of all studies and assist investigators with every aspect of research from study design and budget development through implementation.